Load up some Barnes 50 gr ttsx and give em a go. The faster the better and will easily and ethically kill deer doornail dead.
Gotta be 60gr or more TM-60 gr or more.
DAMMIT Ingwe....Beat me to it again. OTOH SPEER 70 gr in my son's .223 w/14" twist shoots into MOA @ 2970+/-.