Obviously they would kill a deer heck deer have been killed usin surplus fmj ammo. I would however be a little concerned about them shooting through w/o enough energy transfer and ending up having a longer tracking job. I would also have the same concern with 180 gn c&c bullets lets face it deer are just not that big . For deer I think the 150 gr c&c is the best bet in 30 cal. Unless you are using a magnum case.