I run 180 grain barnes TTSX in a 350 remington mag for whitetails. Might be a bit overkill. I want a bullet caliber combo that will run the bullet into the vitals from any possible angle. I am a meat hunter so I will wait to punch a doe through the ribs. If I ever have the chance at a big buck I will take any shot that will eventually run the bullet through the vitals. I am sure I get very little expansion on a broadside lung shot but it works just fine. Don't see why you would not see similar results in the 06 and give the ability to take the less than ideal shot as well. Only drawback is the heavies in 06 drop fairly quick and may limit your range.
