Doubt I'll ever give my Single Six up. I've had it since I was 12 or 13 and must have shot enough critters to fill a boxcar with it. It's not the fanciest revolver in the world but it's accurate, and dependable as a gun can get.
Fully agree, the single 6 is a winner. Had mine for over 25 years without one problem..... Now if I had more $ than I needed, then the answer would be the S&W M41.