I've had difficulties with my 338. Neither the 225 Hornady or Partition shot great; both were around 1.5-1.75 inches at a hundred with a couple different powders and charge weights. Not bad; not great. Factory 225 core-Lokts were horrible. I've settled on a 210g TTSX over 70g of RL-17 in Winchester cases and a Federal 215. I'm averaging MOA to 300 and getting 2900 over my Oehler. The load is under the max listed on the Barnes site but might be a touch warm in my rifle.
My rifle has an extra long throat and roomy chamber. I have to fire form brass and then neck size it to get what I'm getting. If I don't, groups have run about 2 inches or larger.
I will probably continue experimenting in the spring, but for now I'm going with this load. I haven't shot game with it yet but am taking it antelope hunting next week; elk and deer after that. I don't expect problems, (certainly not on antelope
) but if I have any I'll let you know.