You won't be able to "use" it effectively, it is not canister grade powder.
You can use it for fireforming brass or other general uses. I pulled down some 7x57 ammo and used the pull down powder to fireform 7-30 Waters, 257 AI (with pistol bullets) and something else (I forget). I still have a half gallon jug of it left for just these purposes.
If you need to form brass for your 280AI; I would fill the case about 2/3 to 3/4 full and seat a light cast bullet on it. After 2-3 shots, you'll know if you need to go hotter or back off.