I *really* wanted that combination to work for me and my 20" Ruger Alaskan, but alas, it was not to be. I tried charge weights and COAL's all the way up and down the spectrum and tried to stay 'accuracy oriented' and not 'velocity obsessed,' but I never found a sweet spot for my rifle.
4007 SSC gave good (very) accuracy, but velocity was ridiculously low so I kept searching...
The magic combo finally came with Varget:
74 gr Varget, 250gr Barnes TTSX, Fed 215 primer, C.O.A.L. 3.347, Lee Factory Crimp for 2727 fps.
They group like this:
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http://s1322.beta.photobucket.com/u...20Developement/3751_zpscb7ae3c9.jpg.html[/img]
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http://s1322.beta.photobucket.com/u...20Developement/3752_zpsd519ef42.jpg.html[/img]
This same load gave me equally great results with the 270 TSX, 3.300" COAL at around 2650fps - which gives me options if I can't find the TTSX's.
I plan to see how this works with the new (but not yet available) 250 GMX from Hornady when I can get my hands on some.