With a previous 375 I used Hornady 270gr SP. Only killed deer and one elk with them.
I sold my bigger than 400 caliber rifles and have a 375 in process. Should be done soon, so I just ordered some 270gr Hornady's and 270gr TSX's. Hoping to get both bullets to shoot to the same POI.
Figure I'll be all set.
This is my plan in my 375 Ruger, I tried a few 300's and they seemed to up the recoil a notch.