I'm kind of surprised at how popular Sierras are here. They've been accurate for me, but they tend to blow up on critters, making quite a mess. I'm not talking shoulder shots either. I've used the Pro-hunter and Gameking the most, but also the Blitzking and the Matchking on varmints. I haven't been impressed.
Sierra's work just fine if you use "heavy for caliber" pills. I use the gamekings quite a bit and they work great. My favorite elk load uses the 250gr. gk in the 338 win mag. I don't run them super fast either. Just have to be a little smarter when choosing the bullet and load for the game you are after... Pretty simple..