I use 34.5 gr of 4759 over 200gr Rem, Sierra, or Hornady's. Velocity runs around 2200fps with decent enough accuracy as I use it for whitetails in the marsh. 80 yards would be a long shot there, 2 of last years deer were closer to 8 yards.
My Savage smokeless muzzleloader likes this powder, so I am fortunate to have an adequate supply for the foreseeable future.