Towing a trailer from Tok cutoff to ~Kluane is brutal in spots. The north end of the cassiar is simply awesome. If you can find an excuse to drive to Haines, that's a beautiful stretch of road as well. I've towed a ~12000lb boat trailer down the cassiar with no trouble. Steep in places but little traffic. You'll want a good weight distributing hitch or you'll bounce around like a sonofagun on the heaves west of Kluane.

If not towing, expect ~44 hours of seat time between border at Blaine/Sumas and Anchorage. That's 3 pretty hard days.