I've used it in the 243 with bullets of 80 grains and under.. and it has done a very good job for velocity and especially accuracy.....
H 380 is another "old" ignored powder in today's world, were only the latest greatest seems to sell....or is talked about...
I tend to prefer most of the old tried and true stuff...
it is a great powder with uses beyond just the 22.250..
Agreed, I still use H-380 in my 22-250, AND, I don't believe there to be another powder out there that will make a 338-06 sing like H-380 does, damn sure not sing to the tune of 210 gr of Partition bullet at 2800 fps.