I've killed Alaska/Yukon moose with 375 H&H, 300 Win Mag, 30-06, 7MM mag, 308 Winchester, and with a recurve bow. More with a 308 Winchester than anything else. All worked just fine. Worrying about what cartridge to use is much less important than worrying about putting a well-designed projectile in the vitals at a reasonable speed. Just like an arrow from a bow, putting the sharp point in the right place is infinitely more important than how much horsepower is pushing it. Get close (after all, that's what hunting is all about), shoot well, and start carrying meat.