I have a 1-8 .223 that dotes on 50 v-max for its varmint load. It's pushing the 50 harder than a .222 would, and I haven't had one come apart in mid-air that I can tell. With the 1-8 though, I also get the option of 65, 75, and 80grn.

Really like the looks of that 6x45.