I'm using 4350 and the 110gr Accubond in a Pre64 M70 and a custom Roberts built on a 1909 Argentine Mauser action. There is a slight difference in powder charges between the two rifles but it's not much, a grain or a grain and a half IIRC. The M70 will consistently shoot one MOA the custom gun a little better. I get similar results with the 117gr sierra and the 100gr NPT using IMR 4350.