Seafire once told me that a case full, and 60 percent of that case full weight, is a rough "max" for a "no data" workup. The results I've gotten, for BD loads in several 22 cal centerfires with LIGHT bullets, correspond pretty well with that 60 percent suggestion.
You should always work up carefully, a good ways below the "max" as BD is fast, makes stiff pressures, and will make REALLY stiff pressures in a big, scary hurry. Treat it with respect.


Up hills slow,
Down hills fast
Tonnage first and
Safety last.