Flat heads plane in the wind, domes less. Generally you can get a higher weight in a dome. and that also helps with wind. In a 177 I use 10 grainers, and 18 in a 22. The 177 is a Walther LG300 Dominator, and the 22 is an Air Arms SL500. Neither like flat heads. I shoot silhouette, so the ram is at 45 yards.
In the house I shoot a Walther LG400 in 177, but it is made for flat heads, 10 grain domes are less accurate, but it is only 570fps with 8 grainers.