I used the 150's to shoot a few whitetail bucks, a Dall Sheep, an Ibex and a couple of wolves with my .270 Wby. Ranges have been from 70 - 450 yards. Everything has died, but aside from the wolves I've only had one exit wound, which was on a deer at about 300 yards. It was the size of a baseball. With the mess they make out of things, I think they're completely fragmenting on impact - lots of bloodshot meat on the on-side and fragments in the chest cavity.
