Never actually stuck one in a deer, and then I got rid of the rifle, but I do believe that this would knock one to the ground....
Top bullet 450gr, bottom 500gr paper-patch, soft lead, IIRC a Montana Precision Swaging, velocity around 1300 fp, shot into damp sand, Marlin 1895 26" Bbl.....
I had velocity up to around 1600fp with 500grners and recoil, standing, was... um... er.... stout.
PS: RL-7 works great.............