I have a pound of 4166, but have yet to load any ammo with it. My go-to powder in the 300 Savage is WW-748. 41 grains of the stuff under a 180 grain round nose bullet gives 2,450 in a 24" Model EG I own. In shorter barrels, velocity is less, about 2,350 in my 99 E with 20" carbine barrel. I have fooled around with Leverevolution (LVR) powder a bit. I broke down a factory round of Hornady Superformance ammo to find 44.5 grains of a powder looking like LVR. It chronographed 2,700 fps in my 99 F with 22" barrel, and 2,600 fps in the 99 E. Accuracy was nothing to write home about. I tried handloads, and results were about the same as factory ammo.
I have found the Ken Waters Pet Loads to work well. They are the above 180 grain load, and two 150 grain loads: 40 grains of IMR 4064, and 42 grains of WW 748. Velocities are not stellar, but accuracy generally is.
My current effort is using LVR powder with 180 grain bullets, hoping for a meaningful increase in velocity over factory loads (about 2,375 fps). I'm probably chasing my tail.
