As a handloader, if you can't come up with something that shoots better in your rifle than a factory load, you are not doing it right.
I agree with that for most factory ammo I've come across, but I did run across one I had trouble equaling let alone beating.
It was for 308 Winchester, some Norma military/police contract overrun stuff loaded with 168 Match Kings. It shot extremely well in my VTR, 5R, XCR CT, XCR LRT, and 40X.