The 44mag, 450 bushmaster, 460 and 475 are all legal in some special states for deer hunting. Ruger/Lipsey maybe taping into this market.

No 500 S&W mag. Beyond deer?

As stated the 460 may rattle some teeth and I would think the 475 as well. I have seen No1 in very short light configurations in 30-06 that might be a handful for some. On the plus side, the 460 can handle 45 Long Colt and 454. There are plenty of 45LC cowboy loads on the shelf at low cost for fun shooting. Perhaps some one will purchase a 460 and give it review with various power loads.

These pistol rounds might be less risky a purchase where the accuracy expectations are not so high as they would be for something like 243,22-250 etc offerings.