I think that the 22 Nosler is essentially a rebated rim SPC case. So you will probably need the follower from a 6.8 SPC m700 to ensure feeding, if it won't do it off the bat.
I wouldn't go through the trouble except maybe in an AR. The .223 AI gets close enough with cheaper brass. Have heard a lot of sob stories with the early versions splitting cases and not achieving velocity too.
