I shoot the Kenny Jarrett/Borden load just fine in mine but I use Win. Nickle brass that has the largest capacity of any 280 brass and my rifle is long throated for 168 Sierras. We borrowed the reamer from a Silhoutte shooter.

N165, R22, MRP have all been great in the 280AI but am now trying R26 so I can cut down my powder inventory. Looking good so far can equall or exceed velocity of the others and I think I will eventually get back to the same accuracy of the others. But can't go wrong with any of them.

"When you disarm the people, you commence to offend them and show that you distrust them either through cowardice or lack of confidence, and both of these opinions generate hatred." Niccolo Machiavelli