You should be able to load bullets out to a bit longer OAL and increase the pressure in the Browning. This would definately take you out of published loads area but you would be able to get a lot of power out of this combo. You can also load spitzers. 300 grain Barnes Spitzers at 2450 and 400 grains at 2100 should be possible. This is 450 Alaskan Territory!