I've owned/used the 22-250 Ackley fast twist with Hornady 68 OTM, regular 220 Swift with 55gr Trophy Bonded, and the 22/6mm ( .224 TTH) with both the 64gr WW and the 75 Swift Scirocco. All were good killers on hogs, mule deer and Blackbuck antelope. I stopped hunting coyotes like I did and my travels to Texas slowed down a lot, so don't own a hot .22 anymore. My SIL has my Bushmaster Predator AR in .223 and I had given him a tricked out Remington Varminter in 22-250. I have access to those when I go prairie dog shooting. I was amazed at how flat shooting the hot .22s were, and the heavier bullets/fast twist sure bucked the wind well. Surprising really.
