I've never fooled with stabilizing antler. I use Sambar Stag though and hidden tangs. Sambar Stag has very little pith in the center and I remove what it does have and fill the whole thing with Accraglass as my epoxy.(not the gel)

With some woods there is no need for stabilization,and with others it would greatly help. Just for instance,I would not work with unstabilized Ebony but I wouldn't bother with stabilizing Cocobolo,as long as I knew it was dry.