Universal Clays always metered better for me, burned clean, and used about 1 to 1.5 grains less. Same speed. I stopped using Unique.......YMMV
Bob gives excellent advice on all thing 41, and per his advice Unique was the first powder purchased for my 41. But I tend to load very light plinking and target loads (650-700 fps) for the girls and grandkids which burn very dirty with Unique. I got tired of scraping carbon from the muzzle and cylinder face. Universal works very well in this application, as does Titegroup with 165 gr through 210 gr cast bullets
I typically use SR4756 (discontinued), HS-6, and Blue dot for 900-1000 fps loads with 210 gr cast or JHP.
I use W296/H110 for maximum velocity with 210 gr JHP, and the 250 gr cast which is usually reserved for the 7.5 inch Ruger SBH hunter.
