The 10mm is the closest you can get to a 6 shot .41 mag in a medium frame revolver. For hunters/reloaders, the revolver adds advantages to the 10mm in that you can use any bullet shape you want, and any seating depth you desire. That's the advantage. If you don't plan on using different bullets or monkey with seating depth, then there really is no advantage over an auto in 10mm...and certainly some disadvantages.
The choice to use 40 S&W is another advantage.
