I squirrel hunt with .22 match ammo, mostly Eley Tenex and Federal Gold Ultra Match. (I prefer pinpoint bughole accuracy over high velocity, and employ heavy target rifles in order to capitalize on that. Even a solid bullet loafing along at subsonic velocity in the head will snuff out their lights instantly, and a chest hit isn't survivable either.) To that end I sight in at 50 yards, and familiarize myself with compensation requirements for various distances closer and farther away. Frankly, wind and accurate range measurement is more of a challenge out past 50 yards than spinning the elevation knob on the scopes (Unertl and Fecker in my case).
