101 in Washington and Oregon are both excellent drives, all the way down to Eureka CA. That would burn up a week easy.
South of there, like maybe Scotia, you have CA 1 to San Francisco. In a good car, at least two days, maybe three. South of San Fransicko, it's all right on 1 (not 101, which is now a freeway) but much more open. Monterey and Big Sur are impressive, but I turned around at Big Sur and have never been back.
The experience in WA and OR is different than in northern CA, the climate zone changes at Brookings because of the California ocean current.


Up hills slow,
Down hills fast
Tonnage first and
Safety last.