I believe you may be able to shoot 50 gr with that twist. I think
1-9 is pickier than 1-8.
I have chrono'd my 22" .22-250 next to my friends 24" .22-250, both Tikka's with about 25-35 fps difference per inch. The variance was with different factory ammo loaded.
Certainly a minimal loss for my hunting and nothing a handloader can't erase easily. Or factory Superformance ammo can surpass most any other factory load speeds.