I've done 99% of my hunting with a traditional lever gun and have taken antelope with a .25-20, 25-35, .30-30, .45-70 and probably several other calibers if I counted the BLRs. Depending on the terrain, long shots at antelope are not usually necessary. Antelope, in my opinion, are the most fun of all North American big game animals to stalk. I have shot them as close as 30 feet, but 100 yard shots are not uncommon.