Between a Ruger MKIII 22/45 lite and S&W Victory I find myself grabbing the Victory more often. Really like them both. Accuracy edge slightly to Victory. With out the can I shoot the Victory much better I think because of its weight.
By the way, brand new the Ruger needs trigger help, the Victory is pretty good.
I've got two Ruger Mark 4's 22/45's (also had just a plain Mark 4).
The "Ruger needs trigger help" above is an understement. Unaltered mine have ran almost 5 pounds to 6 1/2.
A VQ trigger kit will run you about $120. Spendy, but will take it down to around minus 3 pounds (about where it should have been when it left the factory!).
Jerry