You gotta use enough gun to do the job, man. ...
LOL. Pronghorn don't need that much power. I just wanted to use this rifle on this hunt. I had used a 270 win. for a lot of my previous hunting. Prior to that, I had also used a 300WSM and a 308 Win. They all got the job done with a bullet in the right place.
I had an antelope tag here in Idaho a couple years ago. I keep reading about what a 223 will do on them. I don't have one but I do have a 22-250 so I tried it. Then I got a 75 yd shot broadside. Yes, it floored him, oh yes indeed.