Originally Posted by hanco
I use IMR 4350, hard to try something new when the old powder works so well

Second this. I've been using IMR 4350 with 120gr bullets (Sierra HPBT, now discontinued) in my .25-06 since forever. This is one of the first loads I ever developed when I started re-loading and haven't found a reason to change it. The same load works in both my Winchester M70 and my son's Remington 700.