As mentioned in regards to projectile construction also applies to pistol design/construction.
40-50K loads fired through a Ruger,Taurus or S&W dbl/single action,can not be resized to fit in the c'bored cylinders of a Freedom Arms revolver.
H110
WW296
Accurate #9
Hodgdon Lil Gun
powders perform well in the 454 Casull.