Nothing wrong with the Creedmoor. (Anyone shooting anything with modern powder has no room to complain about "new flavor" cartridges... they all were once and they all had/have obnoxious advocates.)

The 129 grain Hornady Interbond out of a 22" barrel is an absolute sledge hammer for deer. The factory rounds are discontinued but you can still buy the bullets, I believe. Almost total weight retention through bone and all. Major blood trails.