I'm mainly a deer hunter with the occasional black bear and hog thrown in. I used the 405 REM FP and 400 Speer FP quite a bit, pushed up to about 28,000 CUP per Brian Pearces data, but settled on the 300 grain Hornady Hollowpoint at no more than Trapdoor levels. Actually about 1600fps. Expansion is much better and deer drop faster.