Gnoahh: And the 10 pages of "personal experiences" is/will be, a good thing!
Right!
Atse: I have been handloading since I taught myself to do so 60+ years ago when I was 12.
I have probably reloaded Rifle 100,000 cartridges (I am often a high volume Varmint Hunter!) and I have never had a "failure to ignite" centerfire cartridge!
I use mostly Federal primers with a few Remingtons thrown in.
Next time you go to the range try that cartridge again - then take it home and carefully disassemble it to see if you can detect and semi-burnt indications of primer or powder or if in fact something was forgotten (powder?).
Its rare anymore when I hear of one of my friends/Hunting partners having a handload fail to fire/ignite.
In my experience good quality centerfire Rifle primers are VERY reliable.
Maybe it was just a "one of" light firing pin strikes?
Be careful and I hope you figure this one out.
Maybe even try that same cartridge in question in another Rifle of the same caliber to see if it ignites?
Hold into the wind
VarmintGuy