Universal is a great replacement powder, I've used it for decades in multiple cartridges.

It DOES NOT use identical data to Unique, ADI's chart means that they are close to the same burn rate and should both work for the same purposes and charges will be similar.

Use the data here:

http://www.hodgdonreloading.com/data/pistol

'Four legs good, two legs baaaad."
----------------------------------------------
"Jimmy, some of it's magic,
Some of it's tragic,
But I had a good life all the way."
(Jimmy Buffett)

SotG