Lots of people love the Smoky Mountains. I do not.
I would suggest Savannah, Georgia or Charleston, South Carolina.
Brunswick might be nice that time of year.
No offense but I don’t think Brunswick is ever nice. And the coast that time of year is muggy and doesn’t feel like fall in my experience
That time of year I’d be thinking mountains of Georgia, NC, SC or Tennessee. Fly into Atlanta or charlotte and make the 2 hour +/- drive. Tons of places to stay. Entirely dependent on what you want to do, your taste and your budget.
