tape them and use a neoprene cover
I didn't use a neoprene cover, but I did tape my turrets when hunting from a horse last fall. Like the OP, I was using a 2.5-10x42 NXS.
Mine was in Tally lightweights atop a New Haven M70 SS Classic Fwt in a Brown Precision stock (270Win). I took my deer @ 560yds with one shot in the waning hours of the last afternoon of our hunt. The rifle was in/out of the scabbard and logged many miles that week with 0 issues when it was time to put the rifle to work.
