Listen to “manyshots” counsel. I was involved in a project loading the 458/500gr with multiple new powders. In a 22” barrel you can safely exceed 2150. I believe we exceeded 2200.
I will tell you there is a very noticeable increase in recoil with every 50fps. Really noticeable!
Finn Aagaard wrote than at 2000 or so it will blow a bloody big hole in everything.
Go to 2050 maybe 2075 and call it good.