Mule deer.
Have a look at the Speer reloading site with the 250grain Speer hotcore. It's showing 2,700+ fps with the 250grain.
I load the max load for it with CFE223 and get 2,700fps chronoed out of my 25 inch barrel with a 1 in 12 twist. This is without any pressure signs in my rifle. A Stevens 200 converted to 35 Whelen.
With the 225grain accubonds or Woodleigh I get 2,850 to 2,950 fps. These loads were devastating on plains game including Hartman zebra and Oryx, kudu and a large Burchells zebra.
Using newer powders gives the Whelen a big boost without straining it. A 250 grain bullet out of an 8.5 pound rifle at 2,700fps gets your attention.
Bob Nelson