if this is for the lyman clone the best wads to use are the old WWA12 wads either red or white depending on columb height required, these wads are obsolete but still floating around if you can find them. As far a powder I've had good results with 32 grs of Herco, .Note these slugs perform better with the bases filled some guys use hot glue I've elected to use wax (cheaper and easy to apply). Crimped hulls worked better than rolled crimps for me also.
Good luck these are a great slug
