Since you said "do it all" and not whitetail, I'll vote for the NPT too. When my wife got her Remington M7 in 7-08 I loaded the 140 NPT over H4350 and she set out to hunt. Since we move with the Army she has had the chance to kill whitetails, blacktails, hogs, antelope, caribou, black bear, and a moose. She put a second bullet in to a couple animals before they could fall but I think any of the shots she has taken would have been fatal. We did recover 1 of the 2 bullets from the moose, the first one passed through the lungs and the second was under the hide after passing thru on a quartering shot. Load it and shoot it with confidence.