As far as putting anti seize products on your plug, refer to the manufacturer first. Iridium plugs aren't the old school plugs that you cranked down into iron heads. Most are made with silver or chrome plating to be used in aluminum heads. Anti seize causes you to over torque the plugs and potentially cause more damage putting them in than you would taking them out. Modern plugs come out just fine at 100K in modern engines. Of course, in older engines with old style plugs, it's probably a good thing.
