H335 is the fastest and super accurate in the vixen. If the leade is long, then go to the sierra site, they have the 50g semi point on a close out, they shoot like berger bullets. I use Rem 7 1/2 with H335. Walt Berger shot a lot of tiny groups in his 222's before he went to a 6 PPC.

Lots of great bullet in the Vixen. Some were throated long and this is where the 50g Sierra semi point will shine, and they sure dump coyotes hard!

AA2230 is another great powder that will get some serious speed with tiny groups.