AKwolverine: Some time back (1990?) I acquired a pre-64 Winchester Model 70 action that was made the same month (day?) I was born (July 1947) and had it turned into a 280 Remington with a custom 25" medium weight barrel, by a top quality Riflesmith!
It is just about the finest Mule Deer, Elk, Blacktailed Deer, Black Bear, Antelope, Whitetailed Deer, Mt. Goat (and hopefully someday Caribou!) Rifle I have ever had anything to do with!
The transition safety was kept intact and I am glad I did so - it is virtually IMPOSSIBLE to accidentally move that safety lever!
My custom 280 Remington is superbly accurate and the Rifle holds LOTS of bullets.
If you are contemplating building or buying a pre-64 Winchester Model 70 in caliber 280 Remington I certainly HIGHLY recommend you do so.
Good luck in your quest.
Hold into the wind
VarmintGuy